Haixu Tang
Assistant Professor of Informatics
Adjunct Assistant Professor in Computer Science
Affiliated Faculty at Center for Genomics and Bioformatics
Executive committee member of National Center for Glycomics and Glycoproteomics

Office:   Informatics 225

Phone:   (812)-856-1859
Fax:       (812)-856-4764
E-mail:   hatang (at) indiana.edu

Lab: Computational Omics Lab (COL)

Go to Bioinformatics programs at IU Bloomington

Mailing address:

Informatics Building
901 E. 10th St.
Bloomington, IN 47408-3912

Educaltional Background:

Ph.D. in Biochemistry, Shanghai Institute of Biochemistry, Chinese Academy of Sciences.
B.S. in Physics, Department of Physics, Nanjing University, China.

Research Interests:

Algorithmic and statistical problems in Bioinformatics, particularly in

Teaching:

Fall 2004
          I602: Capstone project for bioinformatics master students

Spring 2005
       I590: Topics in Informatics: Introduction to genomics (for non-biology students)

 Spring 2006
       I690: Computational techniques in comparative genomics

Fall 2006
       I617: Informatics in life sciences and chemistry

Spring 2007
       I529: Biological sequence analysis

Awards

  1. NSF Early Career Development (CAREER) Award, 2007.

Books and Book Chapters

  1. S. Kim, H. Tang and E. Mardis, ed. Genome sequencing technology and algorithms, Artech House Publishers (2007). Amazon
  2. H. Tang and S. Kim, Bioinformatics: Mining the massive data from high throughput genomics experiments, pp1-24, in Analysis of Biological Data: A Soft Computing Approach, edited by Sanghamitra Bandyopadhyay, Ujjwal Maulik and Jason T. L. Wang, World Scientific Press (2007).
  3. Y. Ye and H. Tang, Dynamic programming algorithms for sequence and structure comparison, pp9-28, in Bioinformatics Algorithms: Techniques and Applications , edited by Ion Mandoiu and Alexander Zelikovsky , Wiley Press (2008).

Recent Publications:

  1. Z. Jiang, H. Tang, M. Ventura, M. F. Cardone, T. Marques-Bonet, X. She, P. A. Pevzner, E. E. Eichler (2007), Ancestral reconstruction of segmental duplications reveals punctuated cores of human genome evolution. Nat Genet. 39:1361-1368. Pubmed, Commentary on Nature Genetics.
  2. H. Tang (2007) Genome assembly, rearrangement and repeats, Chem Rev., 107(8):3391-3406. Pubmed.
  3. S. H. Bae, H. Tang, J. Wu, J. Xie and S. Kim (2007), dPattern: transcription factor binding site (TFBS) discovery in human genome using a discriminative pattern analysis. 23:2619-2621. Pubmed.
  4. M. Rho, J. H. Choi, S. Kim, M. Lynch and H. Tang (2007), De novo identification of LTR retrotransposons in eukaryotic genomes. BMC Genomics, 8:90. Pubmed.
  5. A. Sundquist, M. Ronaghi, H. Tang, P. A. Pevzner and S. Batzoglou (2007), Whole-genome sequencing and assembly with high-throughput, short-read technologies. PLoS ONE, 2:e484. Pubmed.
  6. Y. Wu, Y. Mechref, I. Klouckova, M. V. Novotny and H. Tang (2007), A computational approach for the identification of site-specific protein glycosylations through ion-trap mass spectrometry, The Third RECOMB Satellite meeting on Proteomics, Lecture Notes in Bioinformatics, 4532:96-107, LNCS online.
  7. P. Alves, R. J. Arnold, M. V. Novotny, P. Radivojac, J. P. Reilly and H. Tang (2007), Advancement in protein inference from shotgun proteomics using peptide detectability. Pacific Symposium on Biocomputing, 12:409-420. Fulltext from PSB online proceeding.
  8. R. Patwardhan, H. Tang, S. Kim and M. Dalkilic (2006), An approximate de Bruijn graph approach to multiple local alignment and motif discovery in protein sequences, The First International Workshop in data mining and bioinformatics, Lecture Notes in Bioinformatics, 4316:158-169.
  9. D. Zhi, B. Raphael, A. Price, H. Tang and P. Pevzner (2006), Identifying repeat domains in large genomes, Genome Biology, 7(1):R7, Pubmed.
  10. D. Zhi, R. Keich, P. Pevzner, S. Heber and H. Tang (2006), Checking for base-calling errors in repeats. IEEE/ACM Transactions on Computational Biology and Bioinformatics, 4(1):54-64, 2007, Pubmed
  11. H. Tang, R. J. Arnold, P. Alves, Z. Xun, D. E. Clemmer, M. V. Novotny, J. P. Reilly and P. Radivojac (2006), A computational approach toward label-free protein quantification using predicted peptide detectability. Bioinformatics, 22(14):e481-488, ISMB 2006. Pubmed.
  12. V. Bafna, H. Tang and Shaojie Zhang (2006), Consensus Folding of Unaligned RNA Sequences Revisited. J. Comp. Biol. 13(2):283-295, Pubmed.
  13. R. J. Arnold, N. Jayasankar, D. Aggarwal, H. Tang and P. Radivojac (2006), A machine learning approach to predicting peptide fragmentation spectra. Proceeding of Pacific Symposium on Biocomputing, 11:219-230, Fulltext from PSB online proceeding.
  14. H. Tang, Y. Mechref and M. Novotny (2005), Automatic Interpretation of MS/MS Spectra of Oligosaccharides. Bioinformatics, 21 Suppl 1:i431-i439, ISMB 2005, Pubmed
  15. V. Bafna, H. Tang and Shaojie Zhang (2005), Consensus Folding of Unaligned RNA Sequences Revisited. Proceedings of the Ninth Annual International Conference on Computational Molecular Biology (RECOMB'05), 172-187, May 2005, Boston, USA, ACM.
  16. B. Raphael, D. Zhi, H. Tang and P. A. Pevzner, A novel method for multiple alignment of sequences with repeats and shuffled elements. Genome Res. 2004, 14: 2336-2346. Pubmed
  17. N. Bandeira, H. Tang, V. Bafna and P. A. Pevzner, Shotgun protein sequencing by tandem mass assembly. Analytical Chemistry, 2004, 76:7221-33. Pubmed
  18. P. A. Pevzner, H. Tang and G. P. Tesler, De novo repeat classification and fragment assembly. Genome Res. 2004 Sep; 14(9): 1786-96. Pubmed
  19. M. Chaisson M, P. A. Pevzner and H. Tang, Fragment assembly with short reads. Bioinformatics. 2004 Sep 1; 20(13): 2067-74. Pubmed
  20. P. A. Pevzner, H. Tang and G. P. Tesler, De novo repeat classification and fragment assembly. Proceedings of the Eighth Annual International Conference on Computational Molecular Biology (RECOMB'04), April 2004, San Diego, USA, ACM Press. 2004 Sep; 14(9): 1786-96.
  21. S. Heber, M. Alekseyev M, S. H. Sze, H. Tang and P. A. Pevzner, Splicing graphs and EST assembly problem. Bioinformatics. 2002; 18 Suppl 1 :S181-8 (ISMB 2002 issue). Pubmed
  22. P. A. Pevzner and H. Tang, Fragment assembly with double-barreled data. Bioinformatics. 2001 Jun;17 Suppl 1:S225-33 (Special ISMB 2001 issue). Pubmed
  23. P. A. Pevzner, H. Tang and M. S. Waterman (2001) A New Approach to Fragment Assembly in DNA Sequencing. Proceedings of the Fifth Annual International Conference on Computational Molecular Biology (RECOMB'01), April 2001, Montreal, Canada, ACM Press.
  24. Q. Tu, H. Tang and D. Ding, MedBlast: searching articles related to a biological sequence. Bioinformatics. 2004,20:75-77. Pubmed
  25. P. A. Pevzner, H. Tang and M. S. Waterman (2001), An Eulerian path approach to DNA fragment assembly. Proc. Natl. Acad. Sci. USA, 98:9748-9753. Pubmed Nature News
  26. S. Kruglyak and H. Tang (2001) A New Estimator of Significance of Correlation in Time Series Data, J. Comp. Biol. 2001,8:463-470. Pubmed
  27. S. Kruglyak and H. Tang (2000) Regulation of Adjecent Yeast Genes. Trends in Genetics, 16:109-111. Pubmed