This is the abstract of a talk prepared for the Oeiras Mathematical and Computational Biology Workshop. June 20, 2003, Instituto Gulbenkian de Ciência
Abstract: Protein modelling / Structural bioinformatics comprises a series of theoretical and computational methodologies, usually based on physical principles, whose aim is to treat the structure and dynamics of biomolecules. These methodologies are quite diverse, and the most well known examples are the molecular dynamics/mechanics simulation methods, continuum electrostatic methods, molecular docking methods and protein structure prediction methods. These methodologies can be applied in the understanding of biological and biotechnological problems. The diverse areas of work carried out in the Protein Modelling work at ITQB will be briefly summarised as illustrations of the wide applicability of this type of methods in modern biological sciences.